A Two-Tailed Phosphopeptide Crystallizes to Form a Lamellar Structure

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A Two‐Tailed Phosphopeptide Crystallizes to Form a Lamellar Structure

The crystal structure of a designed phospholipid-inspired amphiphilic phosphopeptide at 0.8 Å resolution is presented. The phosphorylated β-hairpin peptide crystallizes to form a lamellar structure that is stabilized by intra- and intermolecular hydrogen bonding, including an extended β-sheet structure, as well as aromatic interactions. This first reported crystal structure of a two-tailed pept...

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ژورنال

عنوان ژورنال: Angewandte Chemie

سال: 2017

ISSN: 0044-8249

DOI: 10.1002/ange.201609877